WEB ARTICLE
(Posted 1 October 2001)

Contents
Introduction/Methods
Results
Triggers/Treatments
Discussion
Conclusions
References

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Arachnoiditis: 
Part I - Comparitive Symptom Study
Part II - Red Blood Cell Shape Analysis

by L.O. Simpson & M.G. Anderson

REFERENCES:

1        Simpson L.O., Murdoch J.C., Herbison G.P.  Red cell shape changes following trigger finger fatigue in subjects with chronic tiredness and healthy controls. N.Z. Med.J. 1993. 106: 104-7

2        Simpson. L.O. Red cell shape in health and disease. In:  Physiological Fluid Dynamics III. Swamy N.V.C. and Megha Singh (eds). Varosa Publishing House. New Delhi. 1991.

3        Simpson L.O. Blood from healthy animals and humans contain non-discocytic erythrocytes. Br J Haematol 1989; 73: 561-564

4        Simpson L.O. Chronic tiredness and idiopathic chronic fatigue – a connection? New Jersey Medicine 1992; 89: 211-216

5        Kury P.G., Ramwell P.W., McConnell H.M. The effect of Prostaglandin E-1 and E-2 on the human erythrocyte as monitored by spin labels. Biochim Biophys Res Commun 1974; 56: 478-483

6        Rasmussen H, Lake W, Allen J.C. The effect of catecholamines and prostaglandins upon human and rat erythrocytes. Biochim Biophys Acta 1975; 411: 63-73

7        Simpson L.O. Altered blood rheology in the pathogenesis of Diabetes and other neuropathies. Muscle and Nerve. 1988. 11: 725-744

8        Simpson L.O. The results from red cell shape analyses of blood samples from members of myalgic encephalomyelitis organisations in 4 countries. Journal of Orthomolecular Medicine 1997; 12: 221-226.

9        Smith S., Patron Arachnoiditis Trust, UK. Arachnoiditis – Global Survey, 1999. Unpublished article.

10    Long D.M. Chronic Adhesive Spinal Arachnoidits: Pathogenesis, Prognosis, and Treatment. Neurosurgery Quarterly 1992. 2(4): 296-319

11    Tomlinson D.R., Robinson J.P., Compton A.M., Keen P. Essential Fatty Acid Treatment – effects on nerve conduction, polyol pathway and axonal transport in streptozotocin diabetic rats. Diabetologia. 1989 32 : 655-699

12    Stevens E.J., Lockett M.J., Carrington A.L., Tomlinson D.R. Essential Fatty Acid treatment prevents nerve ischaemia and associated conduction anomalies in rats with experimental diabetes mellitus. Diabetologia. 1993 36 : 397-401

13     Burton C.   http://www.ilbnc.com. 1998: Adhesive Arachnoiditis – Etiology.

14    Smith S. Patron, Arachnoiditis Trust U.K. Spinal Stenosis. Unpublished article.

15    Simpson  L.O. Personal communication.

16    Murukami et al., Effects of intravenous lipoprostaglandin E-1 on neurogenic intermittent claudication. J. Spinal Disord. 1997. (Quoted by Smith.)

17    Martin M.F.R., Tooke J.E. Effects of Prostaglandin E-1 on microvascular haemodynamics in progressive systemic sclerosis. Br J Med 1982; 285: 1688-1690.

18    Pardy B.J., Hoane M.C. et al. Prostaglandin E-1 in severe Raynaud’s phenomenon. Surgery 1982; 92: 953-965.

19    Kyle V., Hazelman B. Prostaglandin E-1 and peripheral vascular disease. Lancet 1983; 2: 282.

20    Manku M.S., Horrobin D.F., Morse N., Kyle V., Jenkins K.  Reduced levels of prostaglandin precursors in the blood of atopic patients: defective delta-6-desaturase function as a biochemical basis. Prost Leuko Med 1982:9:615-628.

21    Birrer, Cynthia. The Medical Cop-Out. Pub. Human and Rousseau, S.A. 1976.